Senescence-accelerated Mouse (SAM): With Special Reference to Development and Pathological Phenotypes.
نویسندگان
چکیده
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منابع مشابه
[Anti-aging studies on the senescence accelerated mouse (SAM) strains].
Senescence accelerated mouse (SAM), a murine model of accelerated senescence, was established by Toshio Takeda and colleagues. SAM consists of series of SAMP (prone) and SAMR (resistant) lines. All SAMP lines (from SAMP1 to SAMP11) are characterized by accelerated accumulation of senile features, earlier onset and faster progress of age-associated pathological phenotypes, such as amyloidosis, i...
متن کاملSenescence-accelerated Mouse (SAM): With Special Reference to Development and Pathobiological Phenotypes
ated aging. J Gerontol Biol Sci 49:B245. Klinger MM, MacCarter GD, Boozer CN. 1996. Body weight and composition in the Sprague Dawley rat: Comparison of three outbred sources. Lab Anim Sci 46:67-70. Lipman RD, Chrisp CE, Hazzard DG, Branson RT. 1996. Pathologic characterization of Brown Norway, Brown Norway X Fischer 344, and Fischer 344 X Brown Norway rats with relation to age. J Gerontol Biol...
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The senescence-accelerated mouse (SAM) is an accelerated aging model that was established through phenotypic selection from a common genetic pool of AKR/J strain of mice. The SAM model was established in 1981, including nine major senescence-accelerated mouse prone (SAMP) substrains and three major senescence-accelerated mouse resistant (SAMR) substrains, each of which exhibits characteristic d...
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ورودعنوان ژورنال:
- ILAR journal
دوره 38 3 شماره
صفحات -
تاریخ انتشار 1997